Today’s post will take a look at one of the most common sterilization methods for single use assemblies, gamma irradiation, and what standards and methods should be followed to call something “sterile”.

This post will give a quick overview of the pros and cons we’ve seen and what makes a single use piece of equipment a good fit.

Holland has been doing research on what hose barb factors create the best unions and this post will highlight key considerations to keep in mind when selecting your next fitting.

This blog post will address what animal components are used in the production of single use bioprocessing equipment, why it is important that animal derived components are avoided where possible, and what products are currently offered in ADC free versions.

Today we will focus on biocompatibility and USP testing. In future posts we will look at other testing requirements not included in USP Class VI that many companies require before they will consider a single use product safe for use with direct product contact.

As with stainless, success with single use systems requires a team effort from procurement, planning, supply chain management, and process engineering.

Silicone tubing is one of the most widely used materials in the high purity process industry. As the industry shifts [...]

To begin, single use tubing is a key part of any single-use system and is critical for secure fluid transport. [...]

For stainless steel guys, the rapid emergence of single use technologies can be pretty scary. At Holland, we saw the [...]

To begin, let us explain first what USP actually stands for:  The United States Pharmacopeia (USP) is a non-government organization [...]

We’re very excited to offer the new AseptiQuik® line of connectors, featuring intuitive designs and robust construction for increased sterile [...]

New Bio-Simplex™ Polypropylene Carboys provide advanced liquid handling and solution storage for a variety of biopharmaceutical applications. Updated design features [...]

At Holland, we keep seeing more and more processes moving from traditional stainless steel applications to single-use processes.  One of [...]

The Bio-Simplex carboys are available with or without an autoclavable spigot. They also feature easy-to-read certified graduation marks with ± 5% accuracy, large molded marks for clearly identifiable volume and material. The Bio-Simplex system–carboy, cap, and spigot is autoclavable.

Quite simply, a sterile connection allows for the dry connection of two separate pathways, while maintaining the independent sterile integrity of both sides. Typical applications might include: the connection to a disposable bag from a bulk tank, mixing of two different types of media together or even simply entering a clean area from a non-clean environment